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產(chǎn)品應(yīng)用

上海奧爾科特生物科技有限公司是研發(fā)、設(shè)計(jì)、制造科學(xué)實(shí)驗(yàn)儀器與系統(tǒng)設(shè)備的專業(yè)企業(yè),自1992年起致力于研發(fā)和生產(chǎn)生命科學(xué)實(shí)驗(yàn)系統(tǒng)與設(shè)備,產(chǎn)品廣泛應(yīng)用,為祖國(guó)的科學(xué)研究事業(yè)做出了貢獻(xiàn)。
奧爾科特公司產(chǎn)品為中國(guó)科學(xué)院、中國(guó)醫(yī)學(xué)科學(xué)院、軍事醫(yī)學(xué)科學(xué)院、北京大學(xué)、清華大學(xué)、復(fù)旦大學(xué)、上海交通大學(xué)、香港大學(xué)、阿斯利康、藥明康德等院校與企業(yè)采用。
奧爾科特公司產(chǎn)品被選用在國(guó)家高新技術(shù)研究發(fā)展項(xiàng)目、國(guó)家973計(jì)劃項(xiàng)目、國(guó)家863計(jì)劃項(xiàng)目、國(guó)家與軍隊(duì)重大計(jì)劃項(xiàng)目等各種重要科學(xué)研究,涵蓋醫(yī)學(xué)、藥物研發(fā)、化學(xué)、物理、生物、運(yùn)動(dòng)、心理、工業(yè)等領(lǐng)域。

在實(shí)驗(yàn)研究中使用奧爾科特的產(chǎn)品,近年發(fā)表的部分科學(xué)研究論著
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Extract of Plantago asiatica L. seeds ameliorates hypertension in spontaneously hypertensive rats by inhibition of angiotensin converting enzyme. Frontiers Pharmacology,30 April2019
Local upregulation of interleukin-1 beta in aortic dissecting aneurysm: correlation with matrix metalloproteinase-2, 9 expression and biomechanical decrease. Interactive CardioVascular and Thoracic Surgery, Volume 28, Issue 3, March 2019, Pages 344–352
Correlation of cardiomyocyte apoptosis with duration of hypertension, severity of hypertension and caspase 3 expression in hypertensive rats. Experimental and Therapeutic Medicine, 2019,Volume17,Issue 4
TLR2 and TLR4 mediate an activation of adipose tissue renin-angiotensin system induced by uric acid, Biochimie, Volume 162, July 2019, Pages 125-133
Protective effect of Xin-Ji-Er-Kang on cardiovascular remodeling in high-salt induced hypertensive mice: Role ofoxidative stress and endothelial dysfunction, Biomedicine & Pharmacotherapy,Volume 115, July 2019, 108937
Dexmedetomidine ameliorates post-CPB lung injury in rats by activating the PI3K/Akt pathway, Journal of Investigative Surgery, 2019,26 Mar 2019
Regulatory T Cells Could Improve Intestinal Barrier Dysfunction in Heatstroke,Inflammation,01 March 2019
Ivabradine improved left ventricular function and pressure overload-induced cardiomyocyte apoptosis in a transverse aortic constriction mouse model, Molecular and cellular biochemistry,January 2019,Volume450,Issue1-2,p25-34
The Dual Neuroprotective-Neurotoxic Effects of Sevoflurane After Hemorrhage Shock Injury, Journal of Surgical Research, 2019 - Volume 235, March 2019, Pages 591-599
Transthoracic Pulmonary Artery Denervation for Pulmonary Arterial Hypertension: Sympathetic Nerve Distribution and Pulmonary Artery Remodeling,Arteriosclerosis, Thrombosis, and Vascular Biology. 2019;39:704–718
Paeoniflorin improves pressure overload-induced cardiac remodeling by modulating the MAPK signaling pathway in spontaneously hypertensive rats, Biomedicine & Pharmacotherapy, Volume 111, March 2019, Pages 695-704
Implantation of engineered conduction tissue in the rat heart,Molecular medicine reports 2019,February5, 2019,Pages2687-2697
Sevoflurane postconditioning protects against myocardial ischemia/reperfusion injury by restoring autophagic flux via an NO-dependent mechanism,Acta Pharmacologica Sinicavolume 40,pages35-45,2019
Acute immune responses are involved in liver and kidney injury in heat stroke,European Journal of Inflammation, April 4, 2019
Effect of olprinone on ischemia-reperfusion induced myocardial injury in rats, Biomedicine & Pharmacotherapy, Volume 111, March 2019, Pages 1005-1012
Repair of Peripheral Nerve Sensory Impairments via the Transplantation of Bone Marrow Neural Tissue-Committed Stem Cell-Derived Sensory Neurons,Cellular and Molecular Neurobiology,April 2019, Volume 39, Issue 3, pp 341-353
ZIPK mediates endothelial cell contraction through myosin light chain phosphorylation and is required for ischemic-reperfusion injury, The FASEB Journal, 10 Jun 2019
Protective effect of Xin Ji Er Kang on cardiovascular remodeling in high salt induced hypertensive mice, Experimental and Therapeutic Medicine, 2019 Volume17 Issue3
Angiotensin-converting enzyme 2 in the rostral ventrolateral medulla regulates cholinergic signaling and cardiovascular and sympathetic responses in hypertensive, Neuroscience bulletin, February 2019, Volume 35, Issue 1, pp 67–78
Total Salvianolic Acid Injection Prevents Ischemia/Reperfusion-Induced Myocardial Injury Via Antioxidant Mechanism Involving Mitochondrial Respiratory, Shock: June 2019,Volume51,Issue6, p745-756
Localized injection of miRNA-21-enriched extracellular vesicles effectively restores cardiac function after myocardial infarction, Theranostics.2019; 9(8): 2346-2360
Chemerin stimulates aortic smooth muscle cell proliferation and migration via activation of autophagy in VSMCs of metabolic hypertension rats, Am J Transl Res 2019;11(3):1327-1342
Crocin attenuation of neurological deficits in a mouse model of intracerebral hemorrhage,Brain Research Bulletin,Volume 150, August 2019, Pages 186-195
Xuezhikang improves the outcomes of cardiopulmonary resuscitation in rats by suppressing the inflammation response through TLR4/NF-κB pathway, Biomedicine & Pharmacotherapy,Volume 114, June 2019, 108817
Activation of nicotinic acetylcholine α7 receptor attenuates progression of monocrotaline-induced pulmonary hypertension in Rats by downregulating the NLRP3, Front.Pharmacol., 26 February 2019
Extract of Plantago asiatica L.seeds ameliorates hypertension in spontaneously hypertensive rats by inhibition of angiotensin converting enzyme, Frontiers in Pharmacology 2019
Effect of isoflurane on myocardial ischemia-reperfusion injury through the p38 MAPK signaling pathway, European Review for Medical and Pharmacological Sciences,2019; 23: 1342-1349
Phenylbutyrate Ameliorates Anxiety Disorder by Inhibiting Endoplasmic Reticulum Stress after Diffuse Axonal Injury, Journal of NeurotraumaVol. 36,No.11,2019
The protective effects of polysaccharide extract from Xin-Ji-Er-Kang formula on Ang II-induced HUVECs injury, L-NAME-induced hypertension and cardiovascular remodeling in mice, BMC Complementary and Alternative Medicine 2019,19:127
Modification of T cells function after restoration of spontaneous circulation in a rat model of cardiac arrest, BioRxiv, 2019 February25, 2019
Royal jelly causes hypotension and vasodilation induced by increasing nitric oxide production, Food Science & Nutrition,Volume7, Issue4, April 2019,Pages 1361-1370
The TLR-4/NF-κB signaling pathway activation in cochlear inflammation of rats with noise-induced hearing loss, Hearing Research, Volume 379, August2019,Pages59-68
The Relationship between Hematoma Expansion Induced by Hypertension and Hyperglycemia and Blood-Brain Barrier Disruption and Its Possible Mechanism:Role of Aquaporin-4 and Connexin43,June5,2019
Using co-axial electrospray deposition to eliminate burst release of simvastatin from microparticles and to enhance induced steogenesis,Journal of Biomaterials Science, Polymer Edition Volume 30, 2019 Issue 5
Protective Effects of 18β-Glycyrrhetinic Acid on Monocrotaline-Induced Pulmonary Arterial Hypertension in Rats, Front. Pharmacol., 22 January 2019
N-Acetyl Serotonin Protects Neural Progenitor Cells Against Oxidative Stress-Induced Apoptosis and Improves Neurogenesis in Adult Mouse Hippocampus Following, Journal of Molecular Neuroscience April 2019, Volume 67, Issue 4, pp 574–588
Identification of RyR2-PBmice and the effects of transposon insertional mutagenesis of the RyR2 gene on cardiac function in mice, PeerJ Biochemistry, Biophysics and Molecular Biology section, 2019
NADPH oxidase 1/4 inhibition attenuates the portal hypertensive syndrome via modulation of mesenteric angiogenesis and arterial hyporeactivity in rats, Clinics and Research in Hepatology and Gastroenterology Volume 43, Issue 3, June 2019, Pages 255-265
CPI-17-mediated contraction of vascular smooth muscle is essential for the development of hypertension in obese mice,Journal of Genetics and Genomics,Volume46, Issue3, 20 March 2019, Pages109-118
Ischemic duration and frequency determines AKI-to-CKD progression monitored by dynamic changes of tubular biomarkers in IRI mice, Front Physiol.2019;10:153.
Repetitive anodal transcranial direct current stimulation improves neurological outcome and survival in a ventricular fibrillation cardiac arrest rat model,Brain Stimulation,Volume12,Issue3, May-June 2019, Pages 659-667
An effective dendritic cell‐based vaccine containing glioma stem‐like cell lysate and CpG adjuvant for an orthotopic mouse model of glioma, Journal of Cancer,2019Volume144,Issue111 June 2019, Pages 2867-2879
Intravenous Transplants of Human Adipose-Derived Stem Cell Protect the Rat Brain From Ischemia-Induced Damage, Journal of Stroke and Cerebrovascular Diseases, Volume 28, Issue 3, March 2019, Pages 595-603
Effects of the combination of Herba Epimedii and Semen Plentaginis on the aortic ACE2/Angiotensin-(1-7)/Mas receptor axis and blood pressure in,Int J Clin Exp Med 2019;12(4):3376-3386
糖尿病大鼠羅庫(kù)溴銨神經(jīng)肌肉阻滯作用的藥效學(xué).中國(guó)醫(yī)學(xué)科學(xué)院學(xué)報(bào),2019,41(02):149-155.
消融Marshall韌帶遠(yuǎn)段對(duì)急性心力衰竭犬心房顫動(dòng)易感性的影響.中國(guó)心臟起搏與心電生理雜志,2019,33(02):138-143.
七氟醚對(duì)低溫灌注大鼠離體心臟電生理穩(wěn)定性的影響.中華麻醉學(xué)雜志,2019(04):440-442.
腦心通膠囊腸吸收液清除DPPH自由基的有效成分辨識(shí)研究.中國(guó)現(xiàn)代中藥,2019,21(04):448-453.
益母草有效成分配伍抗大鼠心肌缺血再灌注損傷作用研究.中國(guó)醫(yī)院藥學(xué)雜志,2019,39(07):708-712.
TCONS_00016478通過PGC1-α/ PPARγ信號(hào)通路影響實(shí)驗(yàn)性房顫兔心房肌能量代謝重構(gòu)的機(jī)制.山東大學(xué)學(xué)報(bào)(醫(yī)學(xué)版),2019,57(04):1-8.
天麻鉤藤湯對(duì)自發(fā)性高血壓模型大鼠的療效及其對(duì)血管壁氧化應(yīng)激的干預(yù)作用.世界中醫(yī)藥,2019,14(03):593-597.
標(biāo)本配穴對(duì)心肌缺血再灌注損傷糖尿病大鼠心肌細(xì)胞的影響及機(jī)制研究.北京中醫(yī)藥大學(xué)學(xué)報(bào),2019,42(03):260-264.
閾下劑量鈣拮抗劑對(duì)小鼠心肌缺血再灌注損傷作用研究.汕頭大學(xué)醫(yī)學(xué)院學(xué)報(bào),2019,32(01):1-4.
t-PA基因修飾的內(nèi)皮祖細(xì)胞對(duì)大鼠急性心肌梗死的治療作用.中國(guó)動(dòng)脈硬化雜志,2019,27(03):204-210.
電針“內(nèi)關(guān)”預(yù)處理對(duì)心肌缺血再灌注損傷大鼠血清代謝物的影響.針刺研究,2019,44(03):176-182
低溫聯(lián)合右美托咪啶對(duì)兔心肌細(xì)胞縫隙連接蛋白43分布的影響.貴州醫(yī)科大學(xué)學(xué)報(bào),2019,44(03):289-292.
電針對(duì)大鼠顱腦損傷后認(rèn)知功能的改善作用.山東中醫(yī)雜志,2019,38(03):261-264
匹諾塞林在t-PA溶栓所致出血轉(zhuǎn)化中的作用.藥學(xué)學(xué)報(bào),2019,54(03):448-453.
天龍通心片對(duì)心肌缺血再灌注損傷及血液流變學(xué)的影響.中國(guó)實(shí)驗(yàn)方劑學(xué)雜志,2019,25(10):41-47.
硫化氫對(duì)膿毒癥大鼠膈肌功能障礙的保護(hù)作用.世界臨床藥物,2019,40(01):29-33.
注射用紅花黃色素經(jīng)TLR-NF-κB炎癥通路抗大鼠MIRI的保護(hù)作用研究.中國(guó)中藥雜志,2019,44(12):2566-2571.
次烏頭堿和甘草苷及甘草次酸配伍對(duì)急性心力衰竭大鼠的動(dòng)態(tài)保護(hù)研究.中華中醫(yī)藥雜志,2019,34(02):746-750.
電針、艾灸預(yù)處理對(duì)心肌缺血大鼠心肌細(xì)胞凋亡和自噬的影響.針刺研究,2019,44(01):31-36.
不同溫度對(duì)離體大鼠心室肌單相動(dòng)作電位、電興奮性的影響.山東醫(yī)藥,2019,59(03):47-50.
丹酚酸A與阿司匹林抗血栓作用的比較研究.藥學(xué)學(xué)報(bào),2019,54(02):301-307.
代謝綜合征合并心肌梗死大鼠模型的建立及氧化應(yīng)激相關(guān)機(jī)制的探討.天津醫(yī)藥,2019,47(01):26-31.
化瘀方抗大鼠心肌纖維化療效及其與氧化應(yīng)激的關(guān)系.重慶醫(yī)學(xué),2019,48(01):6-10.
骨髓間充質(zhì)干細(xì)胞對(duì)心臟驟停后大鼠腦海馬神經(jīng)生長(zhǎng)因子和Caspase-3表達(dá)的影響.中華急診醫(yī)學(xué)雜志,2019(01):30-34.
氫嗎啡酮后處理對(duì)大鼠缺血-再灌注心律失常及心肌縫隙連接蛋白43表達(dá)的影響.醫(yī)藥導(dǎo)報(bào),2019,38(01):9-13.
不同姜制附子對(duì)急性心力衰竭大鼠血流動(dòng)力學(xué)的影響.中華中醫(yī)藥雜志,2019,34(01):332-335.
不同礦物成因禹余糧的止瀉作用.中國(guó)實(shí)驗(yàn)方劑學(xué)雜志,2019,25(05):21-28.
腦心通膠囊腸吸收液保護(hù)過氧化氫致H9c2心肌細(xì)胞損傷的作用機(jī)制及有效藥味篩選.中國(guó)實(shí)驗(yàn)方劑學(xué)雜志,2019,25(04):29-35.
向天果提取物對(duì)腎性高血壓動(dòng)物試驗(yàn)研究.動(dòng)物醫(yī)學(xué)進(jìn)展,2019,40(01):69-73.

 

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